TRV GP V, LLC — Q3 2025 13F-HR

← TRV GP V, LLC

Q3 2025 · 13F-HR

TRV GP V, LLCholdings as filed

Filed 2025-11-13 · accession 0001193125-25-280200

$353.5M

Reported value

Positions

2025-09-30

Period end

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The Brief · TRV GP V, LLC · Q3 2025

AI · grounded in 13F

TRV GP V, LLC established a new position in RAPP valued at $211.9M. The fund also initiated new holdings in SEPN for $116.9M and MAZE for $24.7M. These three additions bring the fund's total AUM to $353.5M.

Holdings as filed

CUSIP	Ticker	Issuer	Value	% port.	Shares	Class	Voting
75383L102	RAPP	RAPPORT THERAPEUTICS, INC.	$211.9M	60.0%	7,135,233	Common	SOLE
81734D104	SEPN	SEPTERNA, INC.	$116.9M	33.1%	6,215,591	Common	SOLE
578784100	MAZE	MAZE THERAPEUTICS, INC.	$24.7M	6.97%	950,800	Common	SOLE

Source: SEC EDGAR · raw 13F holdings as filed. The Class column shows the option type when reported (Put/Call) or Common when the issuer's equity is held directly. 13F discloses long positions only.