MondegarAI
EcoR1 Capital, LLC

Q4 2024 · 13F-HR

EcoR1 Capital, LLCholdings as filed

Filed 2025-02-14 · accession 0000935836-25-000164

$2.65B
Reported value
59
Positions
2024-12-31
Period end
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Holdings as filed

CUSIPTickerIssuerValue% port.SharesClassVoting
03753U106APLSUSDAPELLIS PHARMACEUTICALS INC$379.4M14.3%11,890,843CommonSOLE
98985Y108ZYMEZYMEWORKS INC$220.0M8.32%15,028,079CommonSOLE
22663K107CRNXCRINETICS PHARMACEUTICALS IN$219.3M8.29%4,288,120CommonSOLE
G50871105JAZZJAZZ PHARMACEUTICALS PLC$210.2M7.95%1,706,469CommonSOLE
G72800108PRTAPROTHENA CORP PLC$160.4M6.07%11,584,280CommonSOLE
98401F105XNCRXENCOR INC$141.2M5.34%6,144,767CommonSOLE
717081103PFEPFIZER INC$132.7M5.01%5,000,000CALLSOLE
04335A105ARVNARVINAS INC$128.9M4.87%6,726,491CommonSOLE
032724106ANABANAPTYSBIO INC$104.2M3.94%7,873,448CommonSOLE
803607100SRPTSAREPTA THERAPEUTICS INC$93.6M3.54%770,000CommonSOLE
47103J105JANXJANUX THERAPEUTICS INC$78.7M2.98%1,469,818CommonSOLE
N90064101QUREUNIQURE NV$60.0M2.27%3,400,000CommonSOLE
85205L107SWTXUSDSPRINGWORKS THERAPEUTICS INC$56.4M2.13%1,560,000CommonSOLE
H17182108CRSPCRISPR THERAPEUTICS AG$54.7M2.07%1,389,276CommonSOLE
45257U108IMNMIMMUNOME INC$41.2M1.56%3,879,415CommonSOLE
878972108TECXTECTONIC THERAPEUTIC INC$39.2M1.48%849,143CommonSOLE
87583X109TNGXTANGO THERAPEUTICS INC$32.8M1.24%10,630,736CommonSOLE
88427A107THIRD HARMONIC BIO INC$32.7M1.24%3,182,444CommonSOLE
50127T109KURAKURA ONCOLOGY INC$31.0M1.17%3,557,269CommonSOLE
64135M105NGNENEUROGENE INC$29.1M1.10%1,271,342CommonSOLE
68622P109ORICORIC PHARMACEUTICALS INC$27.6M1.04%3,418,068CommonSOLE
29772L108ETONETON PHARMACEUTICALS INC$24.4M0.92%1,829,603CommonSOLE
55287L101MBXMBX BIOSCIENCES INC$23.2M0.88%1,259,273CommonSOLE
558868105MDGLMADRIGAL PHARMACEUTICALS INC$23.1M0.87%75,000CommonSOLE
92915B106VYGRVOYAGER THERAPEUTICS INC$22.2M0.84%3,917,546CommonSOLE
640979100NMRANEUMORA THERAPEUTICS INC.$22.0M0.83%2,071,450CommonSOLE
14179K101CRGXCARGO THERAPEUTICS INC$21.2M0.80%1,470,000CommonSOLE
61559X104MLTXMOONLAKE IMMUNOTHERAPEUTICS$18.0M0.68%332,522CommonSOLE
37611X209DNAGINKGO BIOWORKS HOLDINGS INC$17.1M0.65%1,743,344CommonSOLE
05370A108RNAGBPAVIDITY BIOSCIENCES INC$16.2M0.61%557,576CommonSOLE
59045L106MERSANA THERAPEUTICS INC$16.2M0.61%11,328,000CommonSOLE
89854M101TCRXTSCAN THERAPEUTICS INC$15.2M0.57%5,000,000CommonSOLE
00653A107ADAPYADAPTIMMUNE THERAPEUTICS PLC$14.8M0.56%27,404,070CommonSOLE
501575104KYMRKYMERA THERAPEUTICS INC$14.1M0.53%350,000CommonSOLE
26818M108DYNDYNE THERAPEUTICS INC$13.1M0.49%555,644CommonSOLE
088786108BCYCBICYCLE THERAPEUTICS PLC$12.7M0.48%910,000CommonSOLE
04683R106AVIRATEA PHARMACEUTICALS INC$11.2M0.42%3,341,653CommonSOLE
23954D109DAWNGBXDAY ONE BIOPHARMACEUTICALS I$10.9M0.41%862,068CommonSOLE
76029N106REPLREPLIMUNE GROUP INC$10.3M0.39%850,341CommonSOLE
01626L204ALGSALIGOS THERAPEUTICS INC$10.2M0.38%255,573CommonSOLE
046513206ATRAATARA BIOTHERAPEUTICS INC$7.1M0.27%532,134CommonSOLE
92539P101VERVE THERAPEUTICS INC$7.0M0.27%1,250,000CommonSOLE
N90064101QUREUNIQURE NV$6.8M0.26%385,000CALLSOLE
31189P102FATEFATE THERAPEUTICS INC$5.0M0.19%3,049,405CommonSOLE
36315X101LKFTGALAPAGOS NV$4.3M0.16%155,006CommonSOLE
019818103ALLOVIR INC$3.9M0.15%408,688CommonSOLE
492327101KROSKEROS THERAPEUTICS INC$3.0M0.11%187,500CommonSOLE
75943R102RLAYRELAY THERAPEUTICS INC$2.6M0.10%641,426CommonSOLE
25056L103DSGNDESIGN THERAPEUTICS INC$2.6M0.10%426,683CommonSOLE
67080N119NUVB/WSNUVATION BIO INC$2.6M0.10%963,333CommonSOLE
37148K100GBIOGBXGENERATION BIO CO$2.2M0.08%2,046,867CommonSOLE
74168J101PRMEPRIME MEDICINE INC$2.0M0.08%700,000CommonSOLE
29772L108ETONETON PHARMACEUTICALS INC$2.0M0.08%151,400CALLSOLE
00032Q104WHWKAADI BIOSCIENCE INC$1.1M0.04%345,253CommonSOLE
91678A107UPBUPSTREAM BIO INC$986,4000.04%60,000CommonSOLE
86889P117SRZNWSURROZEN INC$956,6430.04%66,665CommonSOLE
43906K209HOOKHOOKIPA PHARMA INC$781,6110.03%388,861CommonSOLE
04317A107ARTVARTIVA BIOTHERAPEUTICS INC$417,8460.02%41,453CommonSOLE
61225M102GLUEMONTE ROSA THERAPEUTICS INC$150,5980.01%21,700CALLSOLE

Source: SEC EDGAR · raw 13F holdings as filed. The Class column shows the option type when reported (Put/Call) or Common when the issuer's equity is held directly. 13F discloses long positions only.