Q2 2023 · 13F-HR/A
PERCEPTIVE ADVISORS LLCholdings as filed
Filed 2023-08-24 · accession 0001012975-23-000365
$3.45B
Reported value
95
Positions
2023-06-30
Period end
Holdings as filed
| CUSIP | Ticker | Issuer | Value | % port. | Shares | Class | Voting |
|---|---|---|---|---|---|---|---|
| 03152W109 | AM6 | AMICUS THERAPEUTICS INC | $347.4M | 10.1% | 27,662,917 | Common | SOLE |
| 15678U128 | CERE1EUR | CEREVEL THERAPEUTICS HLDNG I | $320.7M | 9.28% | 10,088,385 | Common | SOLE |
| 53000N108 | LIANY | LIANBIO | $131.2M | 3.80% | 57,558,451 | Common | SOLE |
| 03940C100 | ACLXGBX | ARCELLX INC | $127.0M | 3.68% | 4,016,397 | Common | SOLE |
| 03237H101 | AMLX | AMYLYX PHARMACEUTICALS INC | $105.1M | 3.04% | 4,873,919 | Common | SOLE |
| 462260100 | IOVA | IOVANCE BIOTHERAPEUTICS INC | $98.8M | 2.86% | 14,036,410 | Common | SOLE |
| 01438T106 | ALDX | ALDEYRA THERAPEUTICS INC | $95.2M | 2.76% | 11,350,085 | Common | SOLE |
| 45720L107 | INBXUSD | INHIBRX INC | $94.1M | 2.72% | 3,624,182 | Common | SOLE |
| 925050106 | VRNA | VERONA PHARMA PLC | $93.0M | 2.69% | 4,397,116 | Common | SOLE |
| 670703107 | NUVL | NUVALENT INC | $92.6M | 2.68% | 2,194,821 | Common | SOLE |
| 00973Y108 | AKRO | AKERO THERAPEUTICS INC | $90.6M | 2.62% | 1,940,675 | Common | SOLE |
| 92243G108 | PCVX | VAXCYTE INC | $80.6M | 2.33% | 1,614,122 | Common | SOLE |
| G59665102 | MGTX | MEIRAGTX HLDGS PLC | $76.1M | 2.20% | 11,331,103 | Common | SOLE |
| 03753U106 | APLSUSD | APELLIS PHARMACEUTICALS INC | $74.0M | 2.14% | 812,037 | Common | SOLE |
| 558868105 | MDGL | MADRIGAL PHARMACEUTICALS INC | $70.0M | 2.03% | 302,987 | Common | SOLE |
| 75615P103 | — | REATA PHARMACEUTICALS INC | $68.3M | 1.98% | 670,206 | Common | SOLE |
| 89455T109 | TMCI | TREACE MED CONCEPTS INC | $56.7M | 1.64% | 2,217,250 | Common | SOLE |
| 55234L105 | LYRAGBP | LYRA THERAPEUTICS INC | $52.4M | 1.52% | 12,757,562 | Common | SOLE |
| 92764N102 | VIR | VIR BIOTECHNOLOGY INC | $48.0M | 1.39% | 1,958,264 | Common | SOLE |
| 45258J102 | IMVT | IMMUNOVANT INC | $47.9M | 1.39% | 2,523,783 | Common | SOLE |
| 98420N105 | XENE | XENON PHARMACEUTICALS INC | $47.1M | 1.36% | 1,223,377 | Common | SOLE |
| 000899104 | ADMA | ADMA BIOLOGICS INC | $43.9M | 1.27% | 11,900,255 | Common | SOLE |
| 75382E109 | — | RAPT THERAPEUTICS INC | $42.8M | 1.24% | 2,288,493 | Common | SOLE |
| 92790C104 | VRDN | VIRIDIAN THERAPEUTICS INC | $42.3M | 1.22% | 1,776,386 | Common | SOLE |
| G5960L103 | MDT | MEDTRONIC PLC | $41.1M | 1.19% | 467,000 | Common | SOLE |
| 23257D103 | CBAYUSD | CYMABAY THERAPEUTICS INC | $40.9M | 1.18% | 3,733,255 | Common | SOLE |
| 74366E102 | PTGX | PROTAGONIST THERAPEUTICS INC | $40.6M | 1.18% | 1,469,761 | Common | SOLE |
| 85205L107 | SWTXUSD | SPRINGWORKS THERAPEUTICS INC | $40.3M | 1.17% | 1,537,431 | Common | SOLE |
| N44445109 | IMTX | IMMATICS N.V | $40.3M | 1.17% | 3,491,500 | Common | SOLE |
| 004890109 | ACRV | ACRIVON THERAPEUTICS INC | $39.0M | 1.13% | 3,007,858 | Common | SOLE |
| 63909J108 | NAUT | NAUTILUS BIOTECHNOLOGY INC | $35.3M | 1.02% | 9,111,151 | Common | SOLE |
| 22663K107 | CRNX | CRINETICS PHARMACEUTICALS IN | $35.1M | 1.02% | 1,946,937 | Common | SOLE |
| 254604101 | IRON | DISC MEDICINE INC | $33.0M | 0.95% | 742,838 | Common | SOLE |
| G76279101 | ROIV | ROIVANT SCIENCES LTD | $31.6M | 0.91% | 3,131,736 | Common | SOLE |
| 19240Q201 | COGT | COGENT BIOSCIENCES INC | $31.5M | 0.91% | 2,659,470 | Common | SOLE |
| 413197104 | HRMY | HARMONY BIOSCIENCES HLDGS IN | $31.4M | 0.91% | 891,370 | Common | SOLE |
| 10806X102 | BBIO | BRIDGEBIO PHARMA INC | $30.1M | 0.87% | 1,748,933 | Common | SOLE |
| G31249108 | ESTA | ESTABLISHMENT LABS HLDGS INC | $29.2M | 0.84% | 424,924 | Common | SOLE |
| 92511W108 | — | VERRICA PHARMACEUTICALS INC | $29.1M | 0.84% | 5,038,983 | Common | SOLE |
| 452327109 | ILMN | ILLUMINA INC | $27.2M | 0.79% | 145,000 | Common | SOLE |
| 04016X101 | ARGX | ARGENX SE | $26.9M | 0.78% | 69,000 | Common | SOLE |
| 60468T105 | MRTXEUR | MIRATI THERAPEUTICS INC | $26.0M | 0.75% | 719,103 | Common | SOLE |
| 75943R102 | RLAY | RELAY THERAPEUTICS INC | $24.4M | 0.71% | 1,943,097 | Common | SOLE |
| 87650L103 | TARS | TARSUS PHARMACEUTICALS INC | $23.4M | 0.68% | 1,296,416 | Common | SOLE |
| 77313F106 | RCKT | ROCKET PHARMACEUTICALS INC | $23.2M | 0.67% | 1,168,363 | Common | SOLE |
| 09061G101 | BMRN | BIOMARIN PHARMACEUTICAL INC | $22.8M | 0.66% | 263,207 | Common | SOLE |
| 98985Y108 | ZYME | ZYMEWORKS INC | $20.9M | 0.60% | 2,416,232 | Common | SOLE |
| 12674W109 | CABA | CABALETTA BIO INC | $19.9M | 0.58% | 1,545,000 | Common | SOLE |
| 690145107 | OMGBP | OUTSET MED INC | $19.7M | 0.57% | 902,360 | Common | SOLE |
| 632307104 | NTRA | NATERA INC | $19.7M | 0.57% | 405,269 | Common | SOLE |
| 05464T104 | AXSM | AXSOME THERAPEUTICS INC | $19.5M | 0.56% | 271,493 | Common | SOLE |
| 83422E204 | SLDB | SOLID BIOSCIENCES INC | $18.3M | 0.53% | 3,495,933 | Common | SOLE |
| 04635X102 | CATBUSD | ASTRIA THERAPEUTICS INC | $18.2M | 0.53% | 2,189,462 | Common | SOLE |
| 228903100 | AORT | ARTIVION INC | $16.0M | 0.46% | 931,352 | Common | SOLE |
| 09077A106 | BMEA | BIOMEA FUSION INC | $15.7M | 0.46% | 716,441 | Common | SOLE |
| 46116X101 | ITCIEUR | INTRA-CELLULAR THERAPIES INC | $15.6M | 0.45% | 245,800 | Common | SOLE |
| 604749101 | MIRM | MIRUM PHARMACEUTICALS INC | $15.6M | 0.45% | 601,566 | Common | SOLE |
| 87357P100 | TCMD | TACTILE SYS TECHNOLOGY INC | $15.0M | 0.43% | 602,377 | Common | SOLE |
| 68572M106 | OBIO | ORCHESTRA BIOMED HLDGS INC | $14.4M | 0.42% | 2,052,868 | Common | SOLE |
| 04746L104 | — | ATHIRA PHARMA INC | $14.2M | 0.41% | 4,797,278 | Common | SOLE |
| 05463X106 | AXGN | AXOGEN INC | $13.4M | 0.39% | 1,464,822 | Common | SOLE |
| 36118A100 | — | FUSION PHARMACEUTICALS INC | $12.8M | 0.37% | 2,751,395 | Common | SOLE |
| G72800108 | PRTA | PROTHENA CORP PLC | $12.6M | 0.36% | 184,615 | Common | SOLE |
| 14171W103 | — | CAREMAX INC | $11.9M | 0.34% | 3,817,404 | Common | SOLE |
| 834203309 | SLNO | SOLENO THERAPEUTICS INC | $9.5M | 0.27% | 2,207,753 | Common | SOLE |
| 64125C109 | NBIX | NEUROCRINE BIOSCIENCES INC | $9.4M | 0.27% | 100,050 | Common | SOLE |
| 880881107 | 430 | TERNS PHARMACEUTICALS INC | $9.4M | 0.27% | 1,075,000 | PUT | SOLE |
| 803607100 | SRPT | SAREPTA THERAPEUTICS INC | $9.3M | 0.27% | 81,074 | Common | SOLE |
| G1110E107 | BHVN | BIOHAVEN LTD | $7.7M | 0.22% | 320,820 | Common | SOLE |
| 92686J106 | VKTX | VIKING THERAPEUTICS INC | $7.2M | 0.21% | 441,147 | Common | SOLE |
| 98420X103 | ASNSUSD | X4 PHARMACEUTICALS INC | $6.9M | 0.20% | 3,545,454 | Common | SOLE |
| 46583P102 | — | IVERIC BIO INC | $6.6M | 0.19% | 168,000 | Common | SOLE |
| 515069201 | — | LANDOS BIOPHARMA INC | $6.3M | 0.18% | 1,486,991 | Common | SOLE |
| 90240B106 | TYRA | TYRA BIOSCIENCES INC | $6.1M | 0.18% | 360,000 | Common | SOLE |
| 63009J107 | NBTX | NANOBIOTIX | $5.4M | 0.16% | 1,059,800 | Common | SOLE |
| 91822J202 | LO9A | VBI VACCINES INC CDA | $4.5M | 0.13% | 1,381,355 | Common | SOLE |
| 00445A100 | — | ACELYRIN INC | $4.2M | 0.12% | 200,000 | Common | SOLE |
| 83444K105 | SLGCUSD | SOMALOGIC INC | $3.5M | 0.10% | 1,500,000 | Common | SOLE |
| 50107A104 | KRON1USD | KRONOS BIO INC | $3.0M | 0.09% | 1,752,745 | Common | SOLE |
| 74766Q101 | QTRX | QUANTERIX CORP | $2.9M | 0.08% | 130,000 | Common | SOLE |
| 29415J106 | — | ENVVENO MEDICAL CORPORATION | $2.4M | 0.07% | 781,615 | Common | SOLE |
| 82933R100 | — | SINGULAR GENOMICS SYSTEMS IN | $2.0M | 0.06% | 2,363,214 | Common | SOLE |
| 52187K200 | CYPH | LEAP THERAPEUTICS INC | $1.8M | 0.05% | 586,733 | Common | SOLE |
| 03969K108 | ARQT | ARCUTIS BIOTHERAPEUTICS INC | $1.4M | 0.04% | 300,000 | PUT | SOLE |
| 89422G107 | TVTX | TRAVERE THERAPEUTICS INC | $1.4M | 0.04% | 90,748 | Common | SOLE |
| 60468T105 | MRTXEUR | MIRATI THERAPEUTICS INC | $690,000 | 0.02% | 200,000 | CALL | SOLE |
| 925050106 | VRNA | VERONA PHARMA PLC | $675,000 | 0.02% | 500,000 | CALL | SOLE |
| 730541109 | — | POINT BIOPHARMA GLOBAL INC | $675,000 | 0.02% | 500,000 | PUT | SOLE |
| 78464A870 | XBI | SPDR SER TR | $137,500 | 0.00% | 150,000 | PUT | SOLE |
| 92536C103 | VERUEUR | VERU INC | $106,955 | 0.00% | 89,878 | Common | SOLE |
| 62014P405 | — | MOTUS GI HLDGS INC | $60,318 | 0.00% | 90,027 | Common | SOLE |
| 26886C115 | — | EQRX INC | $42,500 | 0.00% | 250,000 | Common | SOLE |
| 14171W111 | — | CAREMAX INC | $23,400 | 0.00% | 60,000 | Common | SOLE |
| 09075P105 | BTAIEUR | BIOXCEL THERAPEUTICS INC | $10,987 | 0.00% | 439,500 | CALL | SOLE |
| 86889P117 | SRZNW | SURROZEN INC | $10,000 | 0.00% | 166,666 | Common | SOLE |
Source: SEC EDGAR · raw 13F holdings as filed. The Class column shows the option type when reported (Put/Call) or Common when the issuer's equity is held directly. 13F discloses long positions only.