Q2 2024 · 13F-HR
PERCEPTIVE ADVISORS LLCholdings as filed
Filed 2024-08-14 · accession 0001012975-24-000329
$4.20B
Reported value
111
Positions
2024-06-30
Period end
Holdings as filed
| CUSIP | Ticker | Issuer | Value | % port. | Shares | Class | Voting |
|---|---|---|---|---|---|---|---|
| 15678U128 | CERE1EUR | CEREVEL THERAPEUTICS HLDNG I | $441.4M | 10.5% | 10,794,876 | Common | SOLE |
| 03152W109 | AM6 | AMICUS THERAPEUTICS INC | $278.3M | 6.63% | 28,057,456 | Common | SOLE |
| 03940C100 | ACLXGBX | ARCELLX INC | $214.7M | 5.11% | 3,889,739 | Common | SOLE |
| 462260100 | IOVA | IOVANCE BIOTHERAPEUTICS INC | $208.0M | 4.95% | 25,933,142 | Common | SOLE |
| 670703107 | NUVL | NUVALENT INC | $193.4M | 4.60% | 2,549,077 | Common | SOLE |
| 76243J105 | RYTM | RHYTHM PHARMACEUTICALS INC | $141.5M | 3.37% | 3,446,579 | Common | SOLE |
| 92243G108 | PCVX | VAXCYTE INC | $140.6M | 3.35% | 1,862,608 | Common | SOLE |
| 834203309 | SLNO | SOLENO THERAPEUTICS INC | $130.8M | 3.11% | 3,204,976 | Common | SOLE |
| 46116X101 | ITCIEUR | INTRA-CELLULAR THERAPIES INC | $117.6M | 2.80% | 1,716,407 | Common | SOLE |
| N44445109 | IMTX | IMMATICS N.V | $94.0M | 2.24% | 8,086,159 | Common | SOLE |
| 64125C109 | NBIX | NEUROCRINE BIOSCIENCES INC | $89.5M | 2.13% | 649,909 | Common | SOLE |
| 03770N101 | APGE | APOGEE THERAPEUTICS INC | $82.9M | 1.97% | 2,105,636 | Common | SOLE |
| 558868105 | MDGL | MADRIGAL PHARMACEUTICALS INC | $74.1M | 1.77% | 264,600 | Common | SOLE |
| 228903100 | AORT | ARTIVION INC | $71.7M | 1.71% | 2,793,703 | Common | SOLE |
| 00773J202 | SYRE | SPYRE THERAPEUTICS INC | $71.3M | 1.70% | 3,031,018 | Common | SOLE |
| 22663K107 | CRNX | CRINETICS PHARMACEUTICALS IN | $66.1M | 1.57% | 1,476,203 | Common | SOLE |
| 30052C107 | EOLS | EVOLUS INC | $62.4M | 1.49% | 5,753,798 | Common | SOLE |
| 85205L107 | SWTXUSD | SPRINGWORKS THERAPEUTICS INC | $62.3M | 1.48% | 1,652,962 | Common | SOLE |
| 14179K101 | CRGX | CARGO THERAPEUTICS INC | $60.5M | 1.44% | 3,683,004 | Common | SOLE |
| 00211Y506 | ABIOEUR | ARCA BIOPHARMA INC | $59.4M | 1.41% | 15,507,760 | Common | SOLE |
| 04635X102 | CATBUSD | ASTRIA THERAPEUTICS INC | $59.0M | 1.41% | 6,485,420 | Common | SOLE |
| 632307104 | NTRA | NATERA INC | $57.4M | 1.37% | 530,000 | Common | SOLE |
| 92511W108 | — | VERRICA PHARMACEUTICALS INC | $51.8M | 1.23% | 7,099,182 | Common | SOLE |
| G1110E107 | BHVN | BIOHAVEN LTD | $51.6M | 1.23% | 1,485,232 | Common | SOLE |
| 45258J102 | IMVT | IMMUNOVANT INC | $50.8M | 1.21% | 1,923,786 | Common | SOLE |
| G59665102 | MGTX | MEIRAGTX HLDGS PLC | $47.7M | 1.14% | 11,331,103 | Common | SOLE |
| 74366E102 | PTGX | PROTAGONIST THERAPEUTICS INC | $44.0M | 1.05% | 1,268,735 | Common | SOLE |
| 83422E204 | SLDB | SOLID BIOSCIENCES INC | $39.2M | 0.93% | 6,906,646 | Common | SOLE |
| 15102K100 | CELC | CELCUITY INC | $38.7M | 0.92% | 2,362,279 | Common | SOLE |
| G5960L103 | MDT | MEDTRONIC PLC | $38.6M | 0.92% | 490,665 | Common | SOLE |
| 92686J106 | VKTX | VIKING THERAPEUTICS INC | $38.2M | 0.91% | 721,377 | Common | SOLE |
| 03828A101 | APLT | APPLIED THERAPEUTICS INC | $37.4M | 0.89% | 8,005,000 | Common | SOLE |
| 05464T104 | AXSM | AXSOME THERAPEUTICS INC | $37.0M | 0.88% | 459,111 | Common | SOLE |
| 152309100 | CNTA | CENTESSA PHARMACEUTICALS PLC | $35.5M | 0.85% | 3,933,307 | Common | SOLE |
| 87650L103 | TARS | TARSUS PHARMACEUTICALS INC | $35.2M | 0.84% | 1,296,416 | Common | SOLE |
| 925050106 | VRNA | VERONA PHARMA PLC | $35.2M | 0.84% | 2,433,725 | Common | SOLE |
| 00973Y108 | AKRO | AKERO THERAPEUTICS INC | $35.2M | 0.84% | 1,499,897 | Common | SOLE |
| 28036F105 | EWTX | EDGEWISE THERAPEUTICS INC | $33.4M | 0.80% | 1,856,417 | Common | SOLE |
| 004890109 | ACRV | ACRIVON THERAPEUTICS INC | $31.1M | 0.74% | 5,360,858 | Common | SOLE |
| 74006W207 | PRAX | PRAXIS PRECISION MEDICINES I | $31.0M | 0.74% | 750,230 | Common | SOLE |
| 000899104 | ADMA | ADMA BIOLOGICS INC | $31.0M | 0.74% | 2,771,000 | Common | SOLE |
| 10806X102 | BBIO | BRIDGEBIO PHARMA INC | $30.8M | 0.73% | 1,215,346 | Common | SOLE |
| 01438T106 | ALDX | ALDEYRA THERAPEUTICS INC | $30.7M | 0.73% | 9,275,851 | Common | SOLE |
| 63909J108 | NAUT | NAUTILUS BIOTECHNOLOGY INC | $29.5M | 0.70% | 12,594,211 | Common | SOLE |
| 46120E602 | ISRG | INTUITIVE SURGICAL INC | $27.5M | 0.65% | 61,800 | Common | SOLE |
| 04335A105 | ARVN | ARVINAS INC | $27.4M | 0.65% | 1,027,749 | Common | SOLE |
| 77313F106 | RCKT | ROCKET PHARMACEUTICALS INC | $26.8M | 0.64% | 1,246,597 | Common | SOLE |
| 254604101 | IRON | DISC MEDICINE INC | $24.9M | 0.59% | 553,437 | Common | SOLE |
| G5509L101 | LIVN | LIVANOVA PLC | $24.3M | 0.58% | 444,000 | Common | SOLE |
| 156944100 | CGON | CG ONCOLOGY INC | $23.2M | 0.55% | 733,695 | Common | SOLE |
| 98420N105 | XENE | XENON PHARMACEUTICALS INC | $22.7M | 0.54% | 583,256 | Common | SOLE |
| 67576A100 | OCUL | OCULAR THERAPEUTIX INC | $22.7M | 0.54% | 3,324,468 | Common | SOLE |
| 713317105 | PEPG | PEPGEN INC | $22.5M | 0.54% | 1,410,438 | Common | SOLE |
| 92790C104 | VRDN | VIRIDIAN THERAPEUTICS INC | $21.2M | 0.51% | 1,631,828 | Common | SOLE |
| 68572M106 | OBIO | ORCHESTRA BIOMED HLDGS INC | $20.7M | 0.49% | 2,545,881 | Common | SOLE |
| N5749R100 | 2GH | MERUS N V | $17.8M | 0.42% | 300,000 | Common | SOLE |
| 75383L102 | RAPP | RAPPORT THERAPEUTICS INC | $17.4M | 0.41% | 748,183 | Common | SOLE |
| 90240B106 | TYRA | TYRA BIOSCIENCES INC | $16.1M | 0.38% | 1,007,367 | Common | SOLE |
| 21217B100 | CTNM | CONTINEUM THERAPEUTICS INC | $15.8M | 0.38% | 900,000 | Common | SOLE |
| 45720N103 | INBX | INHIBRX BIOSCIENCES INC | $15.1M | 0.36% | 1,064,026 | Common | SOLE |
| 03969K108 | ARQT | ARCUTIS BIOTHERAPEUTICS INC | $14.5M | 0.35% | 1,558,500 | Common | SOLE |
| 04746L104 | — | ATHIRA PHARMA INC | $14.3M | 0.34% | 5,402,964 | Common | SOLE |
| 98985Y108 | ZYME | ZYMEWORKS INC | $14.2M | 0.34% | 1,667,711 | Common | SOLE |
| 230031106 | CGEM | CULLINAN THERAPEUTICS INC | $13.1M | 0.31% | 749,916 | Common | SOLE |
| 74276L105 | PRCT | PROCEPT BIOROBOTICS CORP | $12.9M | 0.31% | 210,659 | Common | SOLE |
| 457669307 | INSM | INSMED INC | $12.1M | 0.29% | 180,000 | Common | SOLE |
| 088786108 | BCYC | BICYCLE THERAPEUTICS PLC | $11.6M | 0.28% | 572,000 | Common | SOLE |
| G4705A100 | ICLR | ICON PLC | $9.8M | 0.23% | 31,250 | Common | SOLE |
| 88023B103 | TEM | TEMPUS AI INC | $9.6M | 0.23% | 275,000 | Common | SOLE |
| 04272N102 | AVBP | ARRIVENT BIOPHARMA INC | $7.7M | 0.18% | 415,000 | Common | SOLE |
| 29286M105 | — | ENGENE HOLDINGS INC | $7.5M | 0.18% | 800,000 | Common | SOLE |
| 82835W108 | SPRY | ARS PHARMACEUTICALS INC | $7.4M | 0.18% | 867,319 | Common | SOLE |
| 04016X101 | ARGX | ARGENX SE | $6.7M | 0.16% | 15,600 | Common | SOLE |
| 019770106 | ALLO | ALLOGENE THERAPEUTICS INC | $6.3M | 0.15% | 2,725,000 | Common | SOLE |
| 92536C103 | VERUEUR | VERU INC | $5.9M | 0.14% | 7,063,277 | Common | SOLE |
| 483497103 | KALV | KALVISTA PHARMACEUTICALS INC | $5.9M | 0.14% | 500,000 | Common | SOLE |
| 75629V104 | RXRX | RECURSION PHARMACEUTICALS IN | $5.8M | 0.14% | 769,230 | Common | SOLE |
| 30233G209 | EYPT | EYEPOINT PHARMACEUTICALS INC | $5.6M | 0.13% | 640,274 | Common | SOLE |
| 45258J102 | IMVT | IMMUNOVANT INC | $5.3M | 0.13% | 200,000 | CALL | SOLE |
| G4444H101 | BBOT | HELIX ACQUISITION CORP II | $5.1M | 0.12% | 500,000 | Common | SOLE |
| 589492107 | MREO | MEREO BIOPHARMA GROUP PLC | $4.5M | 0.11% | 1,253,250 | Common | SOLE |
| 12674W109 | CABA | CABALETTA BIO INC | $4.4M | 0.10% | 585,045 | Common | SOLE |
| 74019P207 | DTIL | PRECISION BIOSCIENCES INC | $4.1M | 0.10% | 426,293 | Common | SOLE |
| 83086J200 | SKYE | SKYE BIOSCIENCE INC | $4.0M | 0.10% | 500,000 | Common | SOLE |
| 896438504 | TRIB | TRINITY BIOTECH PLC | $3.8M | 0.09% | 1,800,000 | Common | SOLE |
| 450056106 | IRTC | IRHYTHM TECHNOLOGIES INC | $3.8M | 0.09% | 35,205 | Common | SOLE |
| 55234L105 | LYRAGBP | LYRA THERAPEUTICS INC | $3.5M | 0.08% | 12,757,562 | Common | SOLE |
| 09075X108 | — | BIODESIX INC | $3.3M | 0.08% | 2,173,880 | Common | SOLE |
| 29415J106 | — | ENVVENO MEDICAL CORPORATION | $3.3M | 0.08% | 623,315 | Common | SOLE |
| 344174107 | FHTX | FOGHORN THERAPEUTICS INC | $3.1M | 0.07% | 544,000 | Common | SOLE |
| 63009J107 | NBTX | NANOBIOTIX | $2.8M | 0.07% | 555,066 | Common | SOLE |
| 14817C107 | FLNA | CASSAVA SCIENCES INC | $2.3M | 0.05% | 183,000 | PUT | SOLE |
| 00091E109 | ABSI | ABSCI CORPORATION | $2.2M | 0.05% | 700,000 | Common | SOLE |
| 78464A870 | XBI | SPDR SER TR | $2.1M | 0.05% | 22,665 | Common | SOLE |
| 98420X103 | ASNSUSD | X4 PHARMACEUTICALS INC | $2.1M | 0.05% | 3,545,454 | Common | SOLE |
| 34962G109 | TOCAEUR | FORTE BIOSCIENCES INC | $1.8M | 0.04% | 3,265,359 | Common | SOLE |
| 761330109 | RVNCEUR | REVANCE THERAPEUTICS INC | $1.5M | 0.04% | 600,000 | Common | SOLE |
| 86366E106 | GPCR | STRUCTURE THERAPEUTICS INC | $1.4M | 0.03% | 34,852 | Common | SOLE |
| 670002401 | NVAX | NOVAVAX INC | $1.3M | 0.03% | 100,000 | PUT | SOLE |
| 31189P102 | FATE | FATE THERAPEUTICS INC | $1.1M | 0.03% | 345,575 | Common | SOLE |
| 501976104 | KYTX | KYVERNA THERAPEUTICS INC | $1.1M | 0.03% | 150,000 | Common | SOLE |
| 269796108 | EGRX | EAGLE PHARMACEUTICALS INC | $970,844 | 0.02% | 173,365 | Common | SOLE |
| 91822J202 | LO9A | VBI VACCINES INC CDA | $832,728 | 0.02% | 1,261,710 | Common | SOLE |
| 87357P100 | TCMD | TACTILE SYS TECHNOLOGY INC | $747,910 | 0.02% | 62,639 | Common | SOLE |
| 87184Q206 | SYRS | SYROS PHARMACEUTICALS INC | $602,451 | 0.01% | 116,754 | Common | SOLE |
| 82933R308 | — | SINGULAR GENOMICS SYSTEMS IN | $599,071 | 0.01% | 70,896 | Common | SOLE |
| 14171W202 | — | CAREMAX INC | $342,174 | 0.01% | 122,643 | Common | SOLE |
| 05463X106 | AXGN | AXOGEN INC | $220,248 | 0.01% | 30,421 | Common | SOLE |
| 76155X118 | RVMDW | REVOLUTION MEDICINES INC | $25,525 | 0.00% | 250,000 | Common | SOLE |
| 86889P117 | SRZNW | SURROZEN INC | $2,767 | 0.00% | 166,666 | Common | SOLE |
| 14171W111 | — | CAREMAX INC | $846 | 0.00% | 60,000 | Common | SOLE |
Source: SEC EDGAR · raw 13F holdings as filed. The Class column shows the option type when reported (Put/Call) or Common when the issuer's equity is held directly. 13F discloses long positions only.