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5AM Venture Management, LLC

Q1 2025 · 13F-HR

5AM Venture Management, LLCholdings as filed

Filed 2025-05-15 · accession 0001085146-25-003293

$264.4M
Reported value
31
Positions
2025-03-31
Period end
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Holdings as filed

CUSIPTickerIssuerValue% port.SharesClassVoting
29384C108TRDAENTRADA THERAPEUTICS INC$39.9M15.1%4,408,379CommonSOLE
29337E102ELVNENLIVEN THERAPEUTICS INC$26.0M9.84%1,322,477CommonSOLE
252828108DNTHDIANTHUS THERAPEUTICS INC$18.6M7.05%1,027,711CommonSOLE
83086J200SKYESKYE BIOSCIENCE INC$15.8M5.96%9,913,168CommonSOLE
N69605108PHVSPHARVARIS N V$12.5M4.74%797,600CommonSOLE
152309100CNTACENTESSA PHARMACEUTICALS PLC$11.9M4.52%830,945CommonSOLE
13463J101CAMPCAMP4 THERAPEUTICS CORP$11.7M4.43%2,927,915CommonSOLE
G1110E107BHVNBIOHAVEN LTD$11.5M4.35%478,972CommonSOLE
61559X104MLTXMOONLAKE IMMUNOTHERAPEUTICS$11.0M4.17%282,313CommonSOLE
92790C104VRDNVIRIDIAN THERAPEUTICS INC$9.9M3.76%736,595CommonSOLE
878972108TECXTECTONIC THERAPEUTIC INC$9.1M3.43%511,660CommonSOLE
15117B202CLDXCELLDEX THERAPEUTICS INC NEW$9.0M3.41%497,270CommonSOLE
90240B106TYRATYRA BIOSCIENCES INC$8.7M3.30%939,298CommonSOLE
29479A108ERASERASCA INC$7.4M2.80%5,405,404CommonSOLE
04317A107ARTVARTIVA BIOTHERAPEUTICS INC$7.1M2.67%2,353,304CommonSOLE
032724106ANABANAPTYSBIO INC$6.7M2.52%357,733CommonSOLE
74006W207PRAXPRAXIS PRECISION MEDICINES I$6.4M2.43%170,000CommonSOLE
G3855L106GHRSGH RESEARCH PLC$6.3M2.39%572,665CommonSOLE
30233G209EYPTEYEPOINT PHARMACEUTICALS INC$5.7M2.15%1,050,000CommonSOLE
92686J106VKTXVIKING THERAPEUTICS INC$4.6M1.73%189,593CommonSOLE
929033108VOR BIOPHARMA INC$4.6M1.73%6,361,723CommonSOLE
86889P208SRZNSURROZEN INC$3.6M1.37%310,000CommonSOLE
74365U107TARAPROTARA THERAPEUTICS INC$3.4M1.29%800,000CommonSOLE
810648105SCPHSCPHARMACEUTICALS INC$3.2M1.19%1,200,647CommonSOLE
75120L100RALLYBIO CORP$2.4M0.90%3,630,724CommonSOLE
00773U207AVU0ADVERUM BIOTECHNOLOGIES INC$2.4M0.90%541,666CommonSOLE
82686Q101SLNSILENCE THERAPEUTICS PLC$1.3M0.51%476,200CommonSOLE
014442107ALECALECTOR INC$1.2M0.46%995,841CommonSOLE
171757206CDTXCIDARA THERAPEUTICS INC$1.2M0.46%56,725CommonSOLE
98943L107ZNTLZENTALIS PHARMACEUTICALS INC$779,1000.29%490,000CommonSOLE
59045L106MERSANA THERAPEUTICS INC$449,1810.17%1,305,000CommonSOLE

Source: SEC EDGAR · raw 13F holdings as filed. The Class column shows the option type when reported (Put/Call) or Common when the issuer's equity is held directly. 13F discloses long positions only.