Q1 2026 · 13F-HR
SR ONE CAPITAL MANAGEMENT, LPholdings as filed
Filed 2026-05-14 · accession 0001193125-26-224136
$915.4M
Reported value
14
Positions
2026-03-31
Period end
The Brief · SR ONE CAPITAL MANAGEMENT, LP · Q1 2026
AI · grounded in 13F
SR ONE CAPITAL MANAGEMENT, LP established a new position in Veradermics, Inc. MANE valued at $151.7M. This addition represents the fund's only change to its portfolio this period. The fund now manages 14 positions with total assets under management of $915.4M.
Holdings as filed
| CUSIP | Ticker | Issuer | Value | % port. | Shares | Class | Voting |
|---|---|---|---|---|---|---|---|
| 03940C100 | ACLXGBX | Arcellx, Inc. | $269.4M | 29.4% | 2,346,630 | Common | SOLE |
| 922967104 | MANE | Veradermics, Inc. | $151.7M | 16.6% | 2,401,868 | Common | SOLE |
| 98937L105 | ZBIO | Zenas BioPharma, Inc | $98.5M | 10.8% | 5,037,854 | Common | SOLE |
| H17182108 | CRSP | CRISPR Therapeutics AG | $97.0M | 10.6% | 2,038,763 | Common | SOLE |
| 25056L103 | DSGN | Design Therapeutics, Inc. | $69.4M | 7.59% | 6,526,476 | Common | SOLE |
| 68622P109 | ORIC | ORIC Pharmaceuticals, Inc. | $58.5M | 6.39% | 4,514,929 | Common | SOLE |
| 022307102 | ALMS | Alumis Inc. | $43.2M | 4.72% | 1,959,896 | Common | SOLE |
| 603170101 | MLYS | Mineralys Therapeutics Inc. | $42.4M | 4.63% | 1,563,966 | Common | SOLE |
| 82835W108 | SPRY | ARS Pharmaceuticals, Inc. | $32.2M | 3.52% | 4,012,903 | Common | SOLE |
| 687604108 | ORKA | Oruka Therapeutics, Inc | $21.1M | 2.31% | 430,330 | Common | SOLE |
| H5870P102 | OCS | Oculis Holding AG | $17.0M | 1.86% | 641,022 | Common | SOLE |
| 65487U108 | NKTX | Nkarta, Inc. | $7.0M | 0.77% | 3,333,333 | Common | SOLE |
| 29286M105 | — | enGene Holdings Inc. | $5.1M | 0.56% | 747,750 | Common | SOLE |
| 90400D108 | RARE | Ultragenyx Pharmaceutical Inc. | $2.9M | 0.32% | 137,753 | Common | SOLE |
Source: SEC EDGAR · raw 13F holdings as filed. The Class column shows the option type when reported (Put/Call) or Common when the issuer's equity is held directly. 13F discloses long positions only.