Q2 2025 · 13F-HR
Samsara BioCapital, LLCholdings as filed
Filed 2025-08-14 · accession 0001415889-25-021908
$488.9M
Reported value
29
Positions
2025-06-30
Period end
The Brief · Samsara BioCapital, LLC · Q2 2025
AI · grounded in 13F
Samsara BioCapital, LLC established a new position in SRRK valued at $198.8M. The fund also initiated new stakes in MLYS for $76.8M and SEPN for $33.3M. Other new additions include KLRS at $30.6M and NGNE at $25.7M. The fund ended the period with 29 positions and total AUM of $488.9M.
Holdings as filed
| CUSIP | Ticker | Issuer | Value | % port. | Shares | Class | Voting |
|---|---|---|---|---|---|---|---|
| 80706P103 | SRRK | SCHOLAR ROCK HLDG CORP | $198.8M | 40.7% | 5,612,896 | Common | SOLE |
| 603170101 | MLYS | MINERALYS THERAPEUTICS INC | $76.8M | 15.7% | 5,674,916 | Common | SOLE |
| 81734D104 | SEPN | SEPTERNA INC | $33.3M | 6.81% | 3,149,128 | Common | SOLE |
| 482929106 | KLRS | KALARIS THERAPEUTICS INC | $30.6M | 6.25% | 11,448,081 | Common | SOLE |
| 64135M105 | NGNE | NEUROGENE INC | $25.7M | 5.25% | 1,717,127 | Common | SOLE |
| 14179K101 | CRGX | CARGO THERAPEUTICS INC | $18.2M | 3.72% | 4,415,689 | Common | SOLE |
| 91678A107 | UPB | UPSTREAM BIO INC | $15.8M | 3.24% | 1,443,231 | Common | SOLE |
| 022307102 | ALMS | ALUMIS INC | $14.4M | 2.95% | 4,801,370 | Common | SOLE |
| 52635N103 | LENZ | LENZ THERAPEUTICS INC | $10.1M | 2.06% | 343,012 | Common | SOLE |
| 697947109 | PVLA | PALVELLA THERAPEUTICS INC NE | $7.7M | 1.57% | 339,743 | Common | SOLE |
| 38341P102 | GOSS | GOSSAMER BIO INC | $7.5M | 1.54% | 6,130,268 | Common | SOLE |
| 03940C100 | ACLXGBX | ARCELLX INC | $6.7M | 1.37% | 101,457 | Common | SOLE |
| 05153U107 | AURA | AURA BIOSCIENCES INC | $6.3M | 1.28% | 1,000,000 | Common | SOLE |
| 65487U108 | NKTX | NKARTA INC | $6.3M | 1.28% | 3,768,035 | Common | SOLE |
| G29687103 | AVDL | AVADEL PHARMACEUTICALS PLC | $6.0M | 1.22% | 675,504 | Common | SOLE |
| 008064206 | JBIO | JADE BIOSCIENCES INC | $5.3M | 1.09% | 531,163 | Common | SOLE |
| 98985Y108 | ZYME | ZYMEWORKS INC | $3.9M | 0.80% | 310,300 | Common | SOLE |
| 76243J105 | RYTM | RHYTHM PHARMACEUTICALS INC | $3.2M | 0.65% | 50,476 | Common | SOLE |
| 918385204 | VTVT | VTV THERAPEUTICS INC | $3.1M | 0.63% | 206,784 | Common | SOLE |
| 21217B100 | CTNM | CONTINEUM THERAPEUTICS INC | $2.3M | 0.48% | 588,816 | Common | SOLE |
| 86889P208 | SRZN | SURROZEN INC | $2.2M | 0.44% | 241,400 | Common | SOLE |
| 869367102 | STRO | SUTRO BIOPHARMA INC | $1.6M | 0.32% | 2,196,814 | Common | SOLE |
| 87583X109 | TNGX | TANGO THERAPEUTICS INC | $1.1M | 0.22% | 210,000 | Common | SOLE |
| 43157M102 | — | HILLEVAX INC | $795,278 | 0.16% | 399,637 | Common | SOLE |
| 880881107 | 430 | TERNS PHARMACEUTICALS INC | $754,758 | 0.15% | 202,348 | Common | SOLE |
| 04317A107 | ARTV | ARTIVA BIOTHERAPEUTICS INC | $440,416 | 0.09% | 291,666 | Common | SOLE |
| 097702203 | BOLT | BOLT BIOTHERAPEUTICS INC | $302,671 | 0.06% | 52,456 | Common | SOLE |
| 67080N119 | NUVB/WS | NUVATION BIO INC | $35,987 | 0.01% | 133,333 | Common | SOLE |
| 86889P117 | SRZNW | SURROZEN INC | $1,810 | 0.00% | 99,999 | Common | SOLE |
Source: SEC EDGAR · raw 13F holdings as filed. The Class column shows the option type when reported (Put/Call) or Common when the issuer's equity is held directly. 13F discloses long positions only.