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Nextech Invest, Ltd.

Q4 2025 · 13F-HR

Nextech Invest, Ltd.holdings as filed

Filed 2026-02-17 · accession 0001595430-26-000002

$1.03B
Reported value
16
Positions
2025-12-31
Period end
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The Brief · Nextech Invest, Ltd. · Q4 2025

AI · grounded in 13F

Nextech Invest, Ltd. established a new position in ENGENE HOLDINGS INC valued at $19.19M. The fund also initiated a position in Monte Rosa Therapeutics Inc GLUE for $4.38M and increased its holdings in Tango Therapeutics Inc TNGX by 31.30%. Conversely, the fund trimmed its stake in Arvinas Inc ARVN by 61.70% and closed its position in Boundless Bio Inc BOLD, exiting the holding for $1.51M.

Holdings as filed

CUSIPTickerIssuerValue% port.SharesClassVoting
76155X100RVMDREVOLUTION MEDICINES INC$605.4M58.5%7,601,087CommonSOLE
90240B106TYRATYRA BIOSCIENCES INC$106.6M10.3%4,055,861CommonSOLE
87583X109TNGXTANGO THERAPEUTICS INC$64.4M6.22%7,266,081CommonSOLE
68622P109ORICORIC PHARMACEUTICALS INC$58.6M5.66%7,162,637CommonSOLE
75943R102RLAYRELAY THERAPEUTICS INC$39.8M3.85%4,701,506CommonSOLE
98985Y108ZYMEZYMEWORKS INC$29.3M2.84%1,113,946CommonSOLE
022307102ALMSALUMIS INC$28.5M2.75%2,915,998CommonSOLE
501575104KYMRKYMERA THERAPEUTICS INC$21.7M2.10%278,896CommonSOLE
29286M105ENGENE HOLDINGS INC$19.2M1.85%2,124,943CommonSOLE
59045L205MRSNMERSANA THERAPEUTICS INC$14.0M1.35%482,689CommonSOLE
230031106CGEMCULLINAN THERAPEUTICS INC$11.8M1.14%1,141,145CommonSOLE
21077P108CNTXCONTEXT THERAPEUTICS INC$10.9M1.05%7,419,355CommonSOLE
82835W108SPRYARS PHARMACEUTICALS INC$7.7M0.74%660,703CommonSOLE
04335A105ARVNARVINAS INC$6.4M0.62%539,394CommonSOLE
82686Q101SLNSILENCE THERAPEUTICS PLC$5.8M0.56%952,400CommonSOLE
61225M102GLUEMONTE ROSA THERAPEUTICS INC$4.4M0.42%279,237CommonSOLE

Source: SEC EDGAR · raw 13F holdings as filed. The Class column shows the option type when reported (Put/Call) or Common when the issuer's equity is held directly. 13F discloses long positions only.