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Paradigm Biocapital Advisors LP

Q4 2023 · 13F-HR

Paradigm Biocapital Advisors LPholdings as filed

Filed 2024-02-14 · accession 0001855655-24-000002

$2.14B
Reported value
30
Positions
2023-12-31
Period end
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Holdings as filed

CUSIPTickerIssuerValue% port.SharesClassVoting
670703107NUVLNUVALENT INC$283.9M13.3%3,858,008CommonSOLE
03940C100ACLXGBXARCELLX INC$203.1M9.51%3,658,624CommonSOLE
04016X101ARGXARGENX SE$160.8M7.53%422,577CommonSOLE
254604101IRONDISC MEDICINE INC$137.8M6.45%2,385,857CommonSOLE
52490G102LEGNLEGEND BIOTECH CORP$114.0M5.34%1,894,644CommonSOLE
68062P106OLMAOLEMA PHARMACEUTICALS INC$110.9M5.19%7,903,600CommonSOLE
92790C104VRDNVIRIDIAN THERAPEUTICS INC$104.4M4.89%4,794,488CommonSOLE
45258D105IMCRIMMUNOCORE HLDGS PLC$99.3M4.65%1,453,883CommonSOLE
15678U128CERE1EURCEREVEL THERAPEUTICS HLDNG I$98.8M4.63%2,330,508CommonSOLE
98420N105XENEXENON PHARMACEUTICALS INC$98.0M4.59%2,127,400CommonSOLE
60468T105MRTXEURMIRATI THERAPEUTICS INC$90.7M4.24%1,543,116CommonSOLE
22663K107CRNXCRINETICS PHARMACEUTICALS IN$82.3M3.85%2,312,919CommonSOLE
05280R100AUTLAUTOLUS THERAPEUTICS PLC$81.2M3.80%12,611,335CommonSOLE
088786108BCYCBICYCLE THERAPEUTICS PLC$67.0M3.14%3,707,001CommonSOLE
641871108AMBRX BIOPHARMA INC$62.0M2.90%4,352,689CommonSOLE
02083G100NVLSEURALPINE IMMUNE SCIENCES INC$60.5M2.83%3,176,743CommonSOLE
04351P101ASNDUSDASCENDIS PHARMA A/S$44.3M2.07%351,700CommonSOLE
04335A105ARVNARVINAS INC$38.3M1.79%931,303CommonSOLE
88322Q108TGTXTG THERAPEUTICS INC$37.1M1.74%2,171,419CommonSOLE
98887Q104ZLABZAI LAB LTD$29.8M1.40%1,091,779CommonSOLE
N44445109IMTXIMMATICS N.V$22.5M1.05%2,136,339CommonSOLE
87650L103TARSTARSUS PHARMACEUTICALS INC$20.8M0.97%1,025,000CommonSOLE
20451W101CMPSCOMPASS PATHWAYS PLC$19.8M0.93%2,265,988CommonSOLE
50127T109KURAKURA ONCOLOGY INC$18.2M0.85%1,262,828CommonSOLE
142038108CRBUCARIBOU BIOSCIENCES INC$16.8M0.78%2,923,851CommonSOLE
929033108VOR BIOPHARMA INC$14.5M0.68%6,457,293CommonSOLE
14179K101CRGXCARGO THERAPEUTICS INC$7.7M0.36%333,333CommonSOLE
98943L107ZNTLZENTALIS PHARMACEUTICALS INC$6.1M0.28%400,000CommonSOLE
008064107AEROVATE THERAPEUTICS INC$3.2M0.15%143,235CommonSOLE
641871108AMBRX BIOPHARMA INC$2.1M0.10%150,000CALLSOLE

Source: SEC EDGAR · raw 13F holdings as filed. The Class column shows the option type when reported (Put/Call) or Common when the issuer's equity is held directly. 13F discloses long positions only.