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Paradigm Biocapital Advisors LP

Q1 2025 · 13F-HR

Paradigm Biocapital Advisors LPholdings as filed

Filed 2025-05-15 · accession 0001855655-25-000007

$2.18B
Reported value
28
Positions
2025-03-31
Period end
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Holdings as filed

CUSIPTickerIssuerValue% port.SharesClassVoting
670703107NUVLNUVALENT INC$373.7M17.1%5,269,433CommonSOLE
03940C100ACLXGBXARCELLX INC$294.7M13.5%4,492,032CommonSOLE
76155X100RVMDREVOLUTION MEDICINES INC$218.5M10.0%6,178,111CommonSOLE
07725L102ONCBEIGENE LTD$181.3M8.30%666,024CommonSOLE
N5749R1002GHMERUS N V$141.8M6.50%3,369,699CommonSOLE
87650L103TARSTARSUS PHARMACEUTICALS INC$134.1M6.14%2,610,197CommonSOLE
28036F105EWTXEDGEWISE THERAPEUTICS INC$96.7M4.43%4,394,556CommonSOLE
47103J105JANXJANUX THERAPEUTICS INC$89.9M4.12%3,329,909CommonSOLE
22663K107CRNXCRINETICS PHARMACEUTICALS IN$65.3M2.99%1,946,168CommonSOLE
92243G108PCVXVAXCYTE INC$64.1M2.93%1,696,481CommonSOLE
254604101IRONDISC MEDICINE INC$60.1M2.75%1,210,971CommonSOLE
19240Q201COGTCOGENT BIOSCIENCES INC$53.7M2.46%8,963,655CommonSOLE
52635N103LENZLENZ THERAPEUTICS INC$38.9M1.78%1,511,932CommonSOLE
03770N101APGEAPOGEE THERAPEUTICS INC$35.9M1.65%961,707CommonSOLE
04016X101ARGXARGENX SE$35.3M1.62%59,679CommonSOLE
23282W605CYTKCYTOKINETICS INC$34.5M1.58%858,664CommonSOLE
457669307INSMINSMED INC$34.4M1.58%451,359CommonSOLE
00773J202SYRESPYRE THERAPEUTICS INC$34.3M1.57%2,127,205CommonSOLE
59267L107METSERA INC$32.4M1.49%1,191,462CommonSOLE
92790C104VRDNVIRIDIAN THERAPEUTICS INC$28.2M1.29%2,095,079CommonSOLE
68062P106OLMAOLEMA PHARMACEUTICALS INC$25.3M1.16%6,741,172CommonSOLE
61559X104MLTXMOONLAKE IMMUNOTHERAPEUTICS$24.5M1.12%627,423CommonSOLE
03969K108ARQTARCUTIS BIOTHERAPEUTICS INC$22.9M1.05%1,465,334CommonSOLE
984241109YMABUSDY-MABS THERAPEUTICS INC$18.8M0.86%4,236,346CommonSOLE
29479A108ERASERASCA INC$14.8M0.68%10,802,354CommonSOLE
28036F105EWTXEDGEWISE THERAPEUTICS INC$11.0M0.50%500,000CALLSOLE
67576A100OCULOCULAR THERAPEUTIX INC$9.6M0.44%1,314,018CommonSOLE
N44445109IMTXIMMATICS N.V$8.6M0.39%1,907,108CommonSOLE

Source: SEC EDGAR · raw 13F holdings as filed. The Class column shows the option type when reported (Put/Call) or Common when the issuer's equity is held directly. 13F discloses long positions only.