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Frazier Life Sciences Management, L.P.

Q3 2025 · 13F-HR

Frazier Life Sciences Management, L.P.holdings as filed

Filed 2025-11-14 · accession 0001892134-25-000012

$3.34B
Reported value
47
Positions
2025-09-30
Period end
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The Brief · Frazier Life Sciences Management, L.P. · Q3 2025

AI · grounded in 13F

Frazier Life Sciences Management, L.P. established a new position in MIRM valued at $498.2M. The fund also initiated new stakes in NAMS for $475M and VRNA for $361.1M. Additional new positions include BBIO at $199.7M and ARQT at $186.1M. Total assets under management stand at $3.3B across 47 positions.

Holdings as filed

CUSIPTickerIssuerValue% port.SharesClassVoting
604749101MIRMMIRUM PHARMACEUTICALS INC$498.2M14.9%6,795,121CommonSOLE
N62509109NAMSNEWAMSTERDAM PHARMA COMPANY$475.0M14.2%16,701,956CommonSOLE
925050106VRNAVERONA PHARMA PLC$361.1M10.8%3,383,950CommonSOLE
10806X102BBIOBRIDGEBIO PHARMA INC$199.7M5.98%3,845,457CommonSOLE
03969K108ARQTARCUTIS BIOTHERAPEUTICS INC$186.1M5.58%9,874,511CommonSOLE
71722W107PHATPHATHOM PHARMACEUTICALS INC$146.7M4.40%12,466,489CommonSOLE
501147102KRYSKRYSTAL BIOTECH INC$121.5M3.64%688,460CommonSOLE
578784100MAZEMAZE THERAPEUTICS INC$118.4M3.55%4,567,274CommonSOLE
55287L101MBXMBX BIOSCIENCES INC$116.4M3.49%6,652,013CommonSOLE
254604101IRONDISC MEDICINE INC$95.1M2.85%1,438,534CommonSOLE
89532M101TRVITREVI THERAPEUTICS INC$93.9M2.81%10,259,409CommonSOLE
87650L103TARSTARSUS PHARMACEUTICALS INC$69.4M2.08%1,167,527CommonSOLE
483497103KALVKALVISTA PHARMACEUTICALS INC$61.4M1.84%5,039,867CommonSOLE
98887Q104ZLABZAI LAB LTD$55.1M1.65%1,627,320CommonSOLE
00847X104AGIOAGIOS PHARMACEUTICALS INC$51.4M1.54%1,279,754CommonSOLE
29479A108ERASERASCA INC$49.6M1.48%22,729,436CommonSOLE
23282W605CYTKCYTOKINETICS INC$48.9M1.47%890,445CommonSOLE
76155X100RVMDREVOLUTION MEDICINES INC$46.6M1.40%997,455CommonSOLE
697947109PVLAPALVELLA THERAPEUTICS INC NE$45.3M1.36%722,400CommonSOLE
805111101SVRASAVARA INC$40.9M1.23%11,462,301CommonSOLE
26818M108DYNDYNE THERAPEUTICS INC$34.4M1.03%2,718,105CommonSOLE
00370M103ABVXABIVAX SA$32.1M0.96%378,300CommonSOLE
05153U107AURAAURA BIOSCIENCES INC$31.5M0.94%5,100,000CommonSOLE
90400D108RAREULTRAGENYX PHARMACEUTICAL IN$29.6M0.89%983,715CommonSOLE
52886X107LXEOLEXEO THERAPEUTICS INC$29.4M0.88%4,424,725CommonSOLE
92025Y103VALNVALNEVA SE$28.0M0.84%2,291,666CommonSOLE
05370A108RNAGBPAVIDITY BIOSCIENCES INC$27.2M0.82%625,000CommonSOLE
04351P101ASNDUSDASCENDIS PHARMA A/S$26.5M0.79%133,333CommonSOLE
G01767105ALKSALKERMES PLC$21.0M0.63%700,647CommonSOLE
589492107MREOMEREO BIOPHARMA GROUP PLC$19.4M0.58%9,440,112CommonSOLE
00973Y108AKROAKERO THERAPEUTICS INC$17.4M0.52%366,784CommonSOLE
92243G108PCVXVAXCYTE INC$17.1M0.51%474,405CommonSOLE
30052C107EOLSEVOLUS INC$16.2M0.48%2,630,665CommonSOLE
25056L103DSGNDESIGN THERAPEUTICS INC$14.7M0.44%1,953,547CommonSOLE
45258D105IMCRIMMUNOCORE HLDGS PLC$14.0M0.42%384,782CommonSOLE
004225108ACADACADIA PHARMACEUTICALS INC$13.1M0.39%613,837CommonSOLE
008064206JBIOJADE BIOSCIENCES INC$12.2M0.37%1,413,280CommonSOLE
045396207ASMBASSEMBLY BIOSCIENCES INC$11.7M0.35%456,249CommonSOLE
00773U207AVU0ADVERUM BIOTECHNOLOGIES INC$9.4M0.28%2,077,431CommonSOLE
89422G107TVTXTRAVERE THERAPEUTICS INC$9.4M0.28%392,092CommonSOLE
N62509117NAMSWNEWAMSTERDAM PHARMA COMPANY$8.6M0.26%500,333CommonSOLE
29286M105ENGENE HOLDINGS INC$7.9M0.24%1,157,380CommonSOLE
05280R100AUTLAUTOLUS THERAPEUTICS PLC$7.5M0.23%4,623,324CommonSOLE
556099109MGNXMACROGENICS INC$5.3M0.16%3,175,665CommonSOLE
82686Q101SLNSILENCE THERAPEUTICS PLC$5.0M0.15%970,130CommonSOLE
019770106ALLOALLOGENE THERAPEUTICS INC$4.8M0.14%3,868,750CommonSOLE
G2545C104CBIOCRESCENT BIOPHARMA INC.$3.2M0.10%272,951CommonSOLE

Source: SEC EDGAR · raw 13F holdings as filed. The Class column shows the option type when reported (Put/Call) or Common when the issuer's equity is held directly. 13F discloses long positions only.