Institutional
Catalio Capital Management, LP
CIK 0001958125
$478.7M
Reported AUM
41
Positions
Q1 2026
Period
2026-05-15
Filed
The Brief · Catalio Capital Management, LP · Q1 2026
AI · grounded in 13F
Catalio Capital Management, LP closed its position in BridgeBio Oncology Therapeutics BBOT for a reduction of $31.4M. The fund established new positions in BridgeBio Pharma Inc BBIO for $32.1M, Definium Therapeutics Inc DFTX for $19.6M, and Incyte Corp INCY for $17.1M. Other significant exits included Eli Lilly & Co LLY at $27.9M and Johnson & Johnson JNJ at $25M. The fund also increased its share counts in UltraGenyx Pharmaceutical In RARE by 423.4% and Terns Pharmaceuticals Inc 430 by 198.7%.
Portfolio · Q1 2026
Top holdings
QoQ vs Q4 2025
| # | Stock | Issuer | Price | Day % | 1Y Gr. | 5Y Gr. | Value | % of book | Δ shares (QoQ) | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | DNTH | DIANTHUS THERAPEUTICS INC | $80.51 | -4.30% | 327.11% | -29.33% | $47.0M | 9.82% | −93,264 | −14.3% |
| 2 | BBIO | BRIDGEBIO PHARMA INC | $66.96 | -0.97% | 75.06% | 26.49% | $32.1M | 6.70% | +432,014 | NEW |
| 3 | ASNDUSD | ASCENDIS PHARMA A/S | — | — | — | — | $29.5M | 6.17% | +9,846 | +8.3% |
| 4 | BMY | BRISTOL-MYERS SQUIBB CO | $57.27 | 1.18% | 24.21% | 3.16% | $25.5M | 5.33% | −227,172 | −35.1% |
| 5 | SNDX | SYNDAX PHARMACEUTICALS INC | $16.97 | -2.16% | 51.44% | 18.93% | $24.4M | 5.09% | −153,137 | −12.8% |
| 6 | GILD | GILEAD SCIENCES INC | $129.16 | -0.02% | 17.90% | 125.52% | $22.8M | 4.77% | −125,407 | −43.3% |
| 7 | 430 | TERNS PHARMACEUTICALS INC | — | — | — | — | $21.6M | 4.50% | +272,073 | +198.7% |
| 8 | DFTX | DEFINIUM THERAPEUTICS INC | $23.55 | -4.23% | 202.31% | -48.69% | $19.6M | 4.10% | +1,037,984 | NEW |
| 9 | SLNO | SOLENO THERAPEUTICS INC | $53.01 | 0.00% | -29.80% | 288.35% | $19.3M | 4.04% | +217,468 | +60.4% |
| 10 | BSX | BOSTON SCIENTIFIC CORP | $48.55 | -0.61% | -52.44% | 6.47% | $18.8M | 3.92% | −61,110 | −17.0% |
| 11 | RARE | ULTRAGENYX PHARMACEUTICAL IN | $21.91 | -6.01% | -41.05% | -72.55% | $17.8M | 3.72% | +688,247 | +423.4% |
| 12 | INCY | INCYTE CORP | $103.26 | 0.86% | 48.87% | 32.36% | $17.1M | 3.58% | +182,101 | NEW |
| 13 | CYTK | CYTOKINETICS INC | $70.51 | -1.35% | 121.30% | 140.84% | $14.2M | 2.97% | −42,880 | −16.6% |
| 14 | NTRA | NATERA INC | $215.31 | -3.06% | 31.48% | 88.01% | $14.2M | 2.96% | +8,634 | +13.9% |
| 15 | CRVS | CORVUS PHARMACEUTICALS INC | $11.23 | 0.99% | 184.40% | 432.06% | $13.0M | 2.73% | +891,933 | NEW |
| 16 | GPCR | STRUCTURE THERAPEUTICS INC | $37.58 | -3.79% | 77.85% | 57.97% | $12.3M | 2.57% | +2,478 | +1.0% |
| 17 | MLYS | MINERALYS THERAPEUTICS INC | $22.85 | -3.52% | 46.96% | 51.28% | $11.9M | 2.48% | +107,192 | +32.3% |
| 18 | EW | EDWARDS LIFESCIENCES CORP | $85.96 | -1.70% | 10.89% | -23.43% | $11.6M | 2.42% | −42,441 | −22.7% |
| 19 | MANE | VERADERMICS INC | $95.01 | 3.63% | 138.28% | 45.19% | $11.0M | 2.29% | +173,582 | NEW |
| 20 | ADPT | ADAPTIVE BIOTECHNOLOGIES COR | $17.01 | 0.65% | 67.49% | -53.90% | $10.0M | 2.10% | −98,411 | −12.0% |
| 21 | HTFL | HEARTFLOW INC | $28.74 | 2.28% | -9.85% | -16.52% | $9.8M | 2.05% | +289,731 | +254.5% |
| 22 | KALV | KALVISTA PHARMACEUTICALS INC | $26.95 | 0.00% | 87.61% | 33.81% | $8.6M | 1.79% | +426,551 | NEW |
| 23 | QURE | UNIQURE NV | $26.45 | -5.50% | 53.16% | -8.82% | $8.0M | 1.68% | +202,771 | +70.3% |
| 24 | IRON | DISC MEDICINE INC | $67.00 | -5.78% | 33.95% | -45.13% | $7.9M | 1.64% | +12,551 | +11.4% |
| 25 | SEPN | SEPTERNA INC | $31.15 | -0.70% | 205.09% | 23.17% | $7.1M | 1.48% | — | HELD |
| 26 | ABVX | ABIVAX SA | $101.53 | -3.24% | 1139.68% | 900.30% | $5.3M | 1.10% | −51,321 | −52.1% |
| 27 | DYN | DYNE THERAPEUTICS INC | $17.04 | -7.44% | 15.92% | -5.70% | $5.1M | 1.07% | −236,761 | −45.6% |
| 28 | ELDN | ELEDON PHARMACEUTICALS INC | $3.41 | -5.28% | 10.71% | -47.46% | $5.1M | 1.06% | +379,996 | +30.2% |
| 29 | KPTI | KARYOPHARM THERAPEUTICS INC | $9.08 | 0.11% | 102.23% | -92.73% | $5.0M | 1.04% | +754,725 | +527.8% |
| 30 | SUPN | SUPERNUS PHARMACEUTICALS | $44.75 | 0.11% | 34.99% | 69.96% | $3.2M | 0.67% | −195,446 | −75.9% |
| 31 | TARA | PROTARA THERAPEUTICS INC | $4.16 | -5.67% | — | — | $3.0M | 0.63% | −866,230 | −59.9% |
| 32 | PHAT | PHATHOM PHARMACEUTICALS INC | $10.06 | -0.69% | — | — | $2.8M | 0.58% | −451,229 | −64.6% |
| 33 | NAMS | NEWAMSTERDAM PHARMA COMPANY | $31.17 | -1.09% | — | — | $2.7M | 0.56% | +83,554 | NEW |
| 34 | TYRA | TYRA BIOSCIENCES INC | $26.43 | -0.79% | — | — | $2.6M | 0.54% | +67,285 | NEW |
| 35 | IMCR | IMMUNOCORE HLDGS PLC | $28.29 | -1.63% | — | — | $2.5M | 0.53% | +84,352 | NEW |
| 36 | GUTS | FRACTYL HEALTH INC | $0.68 | -7.49% | — | — | $2.5M | 0.53% | — | HELD |
| 37 | HYPR | HYPERFINE INC | $1.41 | 2.54% | — | — | $1.4M | 0.30% | — | HELD |
| 38 | MGX | METAGENOMI THERAPEUTICS INC | $1.28 | -3.76% | — | — | $709K | 0.15% | — | HELD |
| 39 | ATAI | ATAIBECKLEY INC | $3.95 | -12.22% | — | — | $697K | 0.15% | +196,858 | NEW |
| 40 | SNSE | SENSEI BIOTHERAPEUTICS INC | $14.65 | -11.75% | — | — | $464K | 0.10% | — | HELD |
| 41 | OM | OUTSET MED INC | $4.58 | -3.17% | — | — | $454K | 0.09% | — | HELD |
| 42 | BBOT | BRIDGEBIO ONCOLOGY THERAPEUT | $7.91 | 1.28% | — | — | — | — | −410,700 | EXITED |
| 43 | LLY | ELI LILLY & CO | $1131.42 | 0.55% | — | — | — | — | −25,923 | EXITED |
| 44 | JNJ | JOHNSON & JOHNSON | $232.77 | 2.02% | — | — | — | — | −120,840 | EXITED |
| 45 | REGN | REGENERON PHARMACEUTICALS | $635.45 | 1.07% | — | — | — | — | −29,797 | EXITED |
| 46 | ISRG | INTUITIVE SURGICAL INC | $422.06 | 0.77% | — | — | — | — | −27,209 | EXITED |
| 47 | ADMA | ADMA BIOLOGICS INC | $8.07 | 1.32% | — | — | — | — | −564,461 | EXITED |
| 48 | ACLXGBX | ARCELLX INC | — | — | — | — | — | — | −156,109 | EXITED |
| 49 | OCUL | OCULAR THERAPEUTIX INC | $8.25 | -6.25% | — | — | — | — | −714,501 | EXITED |
| 50 | OLMA | OLEMA PHARMACEUTICALS INC | $10.21 | -0.97% | — | — | — | — | −267,058 | EXITED |
| 51 | GRAL | GRAIL INC | $59.61 | -0.62% | — | — | — | — | −30,313 | EXITED |
| 52 | FULC | FULCRUM THERAPEUTICS INC | $3.47 | -5.96% | — | — | — | — | −201,301 | EXITED |
| 53 | BLLN | BILLIONTOONE INC | $96.50 | -0.71% | — | — | — | — | −25,505 | EXITED |
| 54 | PVLA | PALVELLA THERAPEUTICS INC NE | $109.39 | 0.66% | — | — | — | — | −10,452 | EXITED |
| 55 | ATAI | ATAI BECKLEY NV | $3.95 | -12.22% | — | — | — | — | −196,858 | EXITED |
Source: SEC EDGAR · accession 0001958125-26-000003. 13F discloses long positions only — shorts, foreign equities, and options are excluded.