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TCG Crossover Management, LLC

Q2 2025 · 13F-HR

TCG Crossover Management, LLCholdings as filed

Filed 2025-08-14 · accession 0001214659-25-012291

$875.5M
Reported value
38
Positions
2025-06-30
Period end
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The Brief · TCG Crossover Management, LLC · Q2 2025

AI · grounded in 13F

TCG Crossover Management, LLC established a new position in CG Oncology Inc CGON valued at $95.4M. The fund also initiated new stakes in Tango Therapeutics Inc TNGX for $55M and Cogent Biosciences Inc COGT for $50M. Other new additions include Ocular Therapeutix Inc OCUL and Cidara Therapeutics Inc CDTX. The fund ended the period with 38 positions and total AUM of $875.5M.

Holdings as filed

CUSIPTickerIssuerValue% port.SharesClassVoting
156944100CGONCG ONCOLOGY INC$95.4M10.9%3,670,206CommonSOLE
87583X109TNGXTANGO THERAPEUTICS INC$55.0M6.28%10,736,000CommonSOLE
19240Q201COGTCOGENT BIOSCIENCES INC$50.0M5.71%6,964,375CommonSOLE
67576A100OCULOCULAR THERAPEUTIX INC$49.4M5.64%5,319,148CommonSOLE
171757206CDTXCIDARA THERAPEUTICS INC$49.0M5.60%1,005,901CommonSOLE
00370M103ABVXABIVAX SA AMERICAN DEPOSITARY SHARES$46.3M5.29%6,056,596CommonSOLE
03237H101AMLXAMYLYX PHARMACEUTICALS INC$38.1M4.35%5,943,812CommonSOLE
152309100CNTACENTESSA PHARMACEUTICALS PLC$38.0M4.34%2,890,816CommonSOLE
359616109FULCFULCRUM THERAPEUTICS INC$36.1M4.13%5,250,000CommonSOLE
26818M108DYNDYNE THERAPEUTICS INC$35.9M4.10%3,766,660CommonSOLE
30233G209EYPTEYEPOINT PHARMACEUTICALS INC$33.6M3.84%3,572,335CommonSOLE
91678A107UPBUPSTREAM BIO INC$30.8M3.51%2,801,763CommonSOLE
805111101SVRASAVARA INC$28.2M3.22%12,362,205CommonSOLE
252828108DNTHDIANTHUS THERAPEUTICS INC$28.0M3.20%1,501,624CommonSOLE
90240B106TYRATYRA BIOSCIENCES INC$27.7M3.17%2,898,103CommonSOLE
254604101IRONDISC MEDICINE INC$24.6M2.81%465,257CommonSOLE
89157D105TRMLTOURMALINE BIO INC$23.6M2.70%1,477,593CommonSOLE
00847X104AGIOAgios Pharmaceuticals, Inc.$23.2M2.65%697,003CommonSOLE
86366E106GPCRSTRUCTURE THERAPEUTICS INC$22.0M2.52%1,063,000CommonSOLE
98401F105XNCRXENCOR INC$19.3M2.20%2,452,138CommonSOLE
82686Q101SLNSILENCE THERAPEUTICS PLC$17.6M2.01%3,033,560CommonSOLE
834203309SLNOSOLENO THERAPEUTICS INC$15.6M1.78%186,250CommonSOLE
04635X102CATBUSDASTRIA THERAPEUTICS INC$14.8M1.69%2,761,861CommonSOLE
75382E208RAPTRAPT Therapeutics, Inc.$13.1M1.50%1,636,275CommonSOLE
88427A107THIRD HARMONIC BIO INC$10.4M1.19%1,915,424CommonSOLE
29337E102ELVNEnliven Therapeutics, Inc.$10.0M1.14%498,000CommonSOLE
55287L101MBXMBX BIOSCIENCES INC$7.4M0.85%650,000CommonSOLE
640268306NKTRNEKTAR THERAPEUTICS$6.9M0.79%266,666CommonSOLE
92840H400VTGNVISTAGEN THERAPEUTICS INC$5.4M0.61%2,676,580CommonSOLE
50015M109KODKODIAK SCIENCES INC$4.3M0.49%1,145,538CommonSOLE
50127T109KURAKURA ONCOLOGY INC$4.2M0.48%735,184CommonSOLE
29384C108TRDAENTRADA THERAPEUTICS INC$3.9M0.45%584,955CommonSOLE
00773U207AVU0ADVERUM BIOTECHNOLOGIES INC$3.9M0.44%1,796,482CommonSOLE
05338F306AVTXAVALO THERAPEUTICS INC$2.4M0.28%483,000CommonSOLE
92332V107VTYXUSDVENTYX BIOSCIENCES INC$676,6570.08%316,195CommonSOLE
008064206JBIOJADE BIOSCIENCES INC$639,5900.07%64,023CommonSOLE
12674W109CABACABALETTA BIO INC$131,9280.02%86,795CommonSOLE
492327101KROSKEROS THERAPEUTICS INC$00CommonSOLE

Source: SEC EDGAR · raw 13F holdings as filed. The Class column shows the option type when reported (Put/Call) or Common when the issuer's equity is held directly. 13F discloses long positions only.