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TCG Crossover Management, LLC

Q3 2025 · 13F-HR

TCG Crossover Management, LLCholdings as filed

Filed 2025-11-17 · accession 0001214659-25-016751

$2.03B
Reported value
40
Positions
2025-09-30
Period end
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The Brief · TCG Crossover Management, LLC · Q3 2025

AI · grounded in 13F

TCG Crossover Management, LLC closed its position in CDTX for a reduction of $48.99M. The fund established a new position in LQDA valued at $38.88M. Other activity included accumulating shares of ABVX by 17.419% and CNTA by 8.498%.

Holdings as filed

CUSIPTickerIssuerValue% port.SharesClassVoting
00370M103ABVXABIVAX SA AMERICAN DEPOSITARY SHARES$603.8M29.7%7,111,596CommonSOLE
156944100CGONCG ONCOLOGY INC$147.8M7.27%3,670,206CommonSOLE
19240Q201COGTCOGENT BIOSCIENCES INC$97.6M4.80%6,798,162CommonSOLE
03237H101AMLXAMYLYX PHARMACEUTICALS INC$84.9M4.17%6,243,812CommonSOLE
152309100CNTACENTESSA PHARMACEUTICALS PLC$76.1M3.74%3,136,480CommonSOLE
87583X109TNGXTANGO THERAPEUTICS INC$71.7M3.53%8,536,196CommonSOLE
67576A100OCULOCULAR THERAPEUTIX INC$71.5M3.52%6,117,232CommonSOLE
252828108DNTHDIANTHUS THERAPEUTICS INC$66.0M3.25%1,676,624CommonSOLE
89157D105TRMLTOURMALINE BIO INC$62.7M3.09%1,311,783CommonSOLE
26818M108DYNDYNE THERAPEUTICS INC$58.4M2.87%4,615,144CommonSOLE
00847X104AGIOAGIOS PHARMACEUTICALS INC$57.4M2.82%1,430,041CommonSOLE
30233G209EYPTEYEPOINT PHARMACEUTICALS INC$50.9M2.50%3,572,335CommonSOLE
359616109FULCFULCRUM THERAPEUTICS INC$48.3M2.38%5,250,000CommonSOLE
805111101SVRASAVARA INC$44.1M2.17%12,362,205CommonSOLE
75382E208RAPTRAPT THERAPEUTICS INC$42.2M2.08%1,636,275CommonSOLE
90240B106TYRATYRA BIOSCIENCES INC$40.5M1.99%2,898,103CommonSOLE
91678A107UPBUPSTREAM BIO INC$39.8M1.96%2,117,103CommonSOLE
53635D202LQDALIQUIDIA TECHNOLOGIES INC$38.9M1.91%1,710,084CommonSOLE
254604101IRONDISC MEDICINE INC$30.7M1.51%465,257CommonSOLE
86366E106GPCRSTRUCTURE THERAPEUTICS INC$29.8M1.46%1,063,000CommonSOLE
98401F105XNCRXENCOR INC$28.8M1.41%2,452,138CommonSOLE
50180M108LBRXLB PHARMACEUTICALS INC$27.6M1.36%1,745,016CommonSOLE
76155X100RVMDREVOLUTION MEDICINES INC$20.4M1.00%436,473CommonSOLE
04635X102CATBUSDASTRIA THERAPEUTICS INC$20.1M0.99%2,761,861CommonSOLE
500946108KRROKORRO BIO INC$19.9M0.98%416,301CommonSOLE
50015M109KODKODIAK SCIENCES INC$18.8M0.92%1,145,538CommonSOLE
00773J202SYRESPYRE THERAPEUTICS INC$18.4M0.91%1,100,582CommonSOLE
82686Q101SLNSILENCE THERAPEUTICS PLC$15.7M0.77%3,033,560CommonSOLE
M96088105URGNUROGEN PHARMA LTD$14.3M0.70%717,347CommonSOLE
04335A105ARVNARVINAS HOLDING CO LLC$13.8M0.68%1,617,365CommonSOLE
61023L207MNPRMONOPAR THERAPEUTICS INC$12.5M0.61%153,000CommonSOLE
55287L101MBXMBX BIOSCIENCES INC$11.4M0.56%650,000CommonSOLE
92840H400VTGNVISTAGEN THERAPEUTICS INC$9.5M0.47%2,676,580CommonSOLE
75943R102RLAYRELAY THERAPEUTICS INC$9.5M0.46%1,810,351CommonSOLE
00773U207AVU0ADVERUM BIOTECHNOLOGIES INC$7.6M0.37%1,668,174CommonSOLE
05338F306AVTXAVALO THERAPEUTICS INC$6.1M0.30%483,000CommonSOLE
H0036K147ADCTADC THERAPEUTICS SA$5.6M0.27%1,390,175CommonSOLE
713317105PEPGPEPGEN INC$5.5M0.27%1,200,000CommonSOLE
29384C108TRDAENTRADA THERAPEUTICS INC$3.4M0.17%584,955CommonSOLE
92332V107VTYXUSDVENTYX BIOSCIENCES INC$983,3660.05%316,195CommonSOLE

Source: SEC EDGAR · raw 13F holdings as filed. The Class column shows the option type when reported (Put/Call) or Common when the issuer's equity is held directly. 13F discloses long positions only.